| artist | hits (month) | hits (total) |
| S & K | 121 | 129 |
| S Club | 115 | 122 |
| S Club 7 | 307 | 692 |
| S Club 8 | 291 | 425 |
| S Club Juniors | 150 | 214 |
| S ka oito | 143 | 151 |
| S O S Band | 143 | 159 |
| S. Gary | 157 | 161 |
| S.G. Swain | 220 | 334 |
| S.H.E. | 138 | 154 |
| S.L.A.B. | 212 | 316 |
| S.N.F.U. | 148 | 150 |
| S.o.a.p | 114 | 119 |
| S.O.A.P. | 123 | 127 |
| S.O.D. | 178 | 307 |
| S.P.O.C.K | 185 | 243 |
| S.P.O.C.K. | 140 | 175 |
| S.T.A.R.S. | 113 | 118 |
| S.T.U.N | 146 | 177 |
| S.W.V | 125 | 151 |
| S.W.V. | 145 | 150 |
| Sa-Fire | 117 | 125 |
| Saafir | 145 | 149 |
| Saafir The Saucee Nomad | 160 | 165 |
| Saan Supa Crew | 192 | 231 |
| Sabac | 157 | 174 |
| Sabbat | 122 | 126 |
| Sabina Joaquin | 243 | 312 |
| SABRINA | 132 | 143 |
| Sacha Distel | 155 | 165 |
| Sacred Harp Singers | 128 | 135 |
| Sacred Reich | 157 | 176 |
| Sacrifice | 116 | 133 |
| Sadao Watanabe | 139 | 148 |
| Saddle Club | 162 | 171 |
| Sade | 215 | 466 |
| Sadus | 138 | 153 |
| Safaris | 139 | 147 |
| Saffire - The Uppity Blues Women | 153 | 162 |
| Saga | 126 | 128 |
| Sage Francis | 193 | 401 |
| Sahara Hotnights | 151 | 169 |
| Sahlene | 129 | 134 |
| Saian Supa Crew | 210 | 308 |
| Saigon | 184 | 217 |
| Saigon Kick | 226 | 243 |
| Saiko | 227 | 335 |
| Sailcat | 137 | 148 |
| Sailor | 172 | 195 |
| Sailor Moon | 125 | 161 |
Artists begining with the letter 'S'
